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Percy Julian was a pioneering chemist who was not allowed to attend high school but went on to earn his Ph. His research at academic and corporate institutions led to the chemical synthesis of drugs to treat glaucoma and arthritis, and although his race presented challenges at every turn, he is regarded as one of the most influential chemists in American history. He attended school through the eighth grade but there were no high schools open to Black students. He applied to DePauw University in Greencastle, Indiana, where he had to take high school-level classes in the evening to get him up to the academic level of his peers. In spite of this challenging beginning, he graduated first in his class, with Phi Beta Kappa honors. After college, Julian accepted a position as a chemistry instructor at Fisk University. He traveled for several years, teaching at Black colleges, before obtaining his Ph. With his doctorate in hand, he returned to DePauw to continue his research. In , he earned international acclaim by synthesizing physostigmine from the calabar bean to create a drug treatment for glaucoma, but in spite of his success, the university refused to make him a full professor because of his race.